Original Article

Combined Radiofrequency and Ultrasonic Cavitation Therapy Does not Have Adverse Effects on Hematological and Liver Markers in Overweight Women


Background: Although dietary management is the principle intervention for treating obesity, noninvasive body-contouring methods are also gaining currency. We aimed to explore the effects of combined radiofrequency (RF) and ultrasound (US) body contouring on anthropometric indices, hematological markers, and anti-HSP27 levels in overweight females.
Methods: In this randomized control clinical trial, fifty overweight females were enrolled and divided into two groups. Each participant was prescribed a diet with a daily calorie deficit of 500 kcal. RF and US were each used once a week for 5 weeks in the intervention group. Anthropometric and hematological markers were measured in all subjects before and after the intervention.
Results: Abdominal circumference (AC), waist circumference (WC), body mass index, and body fat mass were reduced significantly in both groups (p < 0.001). However, the mean reduction in AC (p < 0.05) and WC (p < 0.001) were significantly greater in the intervention group compared with the control group. Moreover, levels of WBC, HCT, Hb, MCV, and MCH were significantly reduced after the RF-US intervention, although all the changes were in the normal range, suggesting that this therapy did not have adverse effects on hematological parameters. Also, the level of anti-HSP27 did not show any significant change.
Conclusion: Our study suggests that body-contouring devices based on RF and US cavitation reduce measures of adiposity and do not have adverse effects on hematological factors, liver function markers, and HSP27 level in overweight women. Further investigations are required to explore the value of this method in a larger multicenter setting.

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IssueVol 3, No 4 (Autumn 2017) QRcode
SectionOriginal Article(s)
Overweight Radiofrequency Ultrasound cavitation Hemoglobin; Hematocrit;

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How to Cite
Mohammadzadeh E, Arabpour Dahoue M, Sahebkar A, Kianoush T, Avan A, Nezafati P, Sadabadi F, Ghazizadeh H, Safar Soflaei S, Mohammadzadeh M, Nasrfard S, Safarian M, Norouzi A, Parizadeh seyed MR, Ghayour-Mobarhan M. Combined Radiofrequency and Ultrasonic Cavitation Therapy Does not Have Adverse Effects on Hematological and Liver Markers in Overweight Women. J Nutr Sci & Diet. 2017;3(4):14-21.