Original Article

Fruit, vegetable, and dietary antioxidant intake and age-related cataract risk: A case-control study


Aim: This study was done to evaluate the relationship between dietary intake of some macronutrients, carotenoids, vitamins C, E, and A, and selenium and the risk of cataract.
Methods: In this case-control study, dietary intakes of 97 cataract patients and 198 controls were assessed using a valid semi-quantitative food frequency questionnaire. Cataract was diagnosed using a slit-lamp examination and defined as any lens opacity in either eye. The associations between cataract incidence and quartiles of macronutrient and micronutrient intakes were investigated using logistic regression models.
Results: After adjusting for the effects of confounding variables, the risk of cataract was significantly low in the highest nutrient intake quartile relative to the lowest quartile for fruits (OR = 0.15; 95% CI = 0.05-0.30) and vegetables (OR= 0.20; 95% CI = 0.08-0.40). We found significant, inverse associations of cataract with high dietary intake of vitamin C (OR = 0.22; 95% CI = 0.09-0.54), alpha-carotene (OR = 0.24; 95% CI = 0.10-0.58), beta-carotene (OR = 0.15; 95% CI = 0.05-0.39), lutein/zeaxanthin (OR = 0.19; 95% CI = 0.08-0.45), and beta-cryptoxanthin (OR = 0.05; 95% CI = 0.01-0.15).
Conclusion: High daily intakes of fruits and vegetables and some dietary antioxidants might be associated with a decrease in cataract risk in Tehran, Iran.

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IssueVol 3, No 2 (Spring 2017) QRcode
SectionOriginal Article(s)
Cataract Carotenoids Fruit Vegetables

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How to Cite
Ghanavati M, Alipour M, Khodaparast-Zavareh M, Sarli R, Rashidkhani B. Fruit, vegetable, and dietary antioxidant intake and age-related cataract risk: A case-control study. J Nutr Sci & Diet. 2017;3(2):15-22.