Dietary intake of vitamin D and metabolic syndrome after 3-year follow-up: Tehran lipid and glucose study
-
Sakineh Shab-Bidar
,
Firoozeh Hosseini-Esfahani
,
Hossein Delshad
,
Golaleh Asghari
,
Parvin Mirmiran
,
Fereidoun Azizi
Abstract
Background: The aim of this study was to examine the association between dietary intakes of vitamin D and the metabolic syndrome (MetS) in Tehranian adults, Iran.
Methods: In this population-based prospective study, a sample of 2357 subjects, aged 20-74 years, who had completed a validated food frequency questionnaire, were studied. MetS was defined according to the modified guidelines of the National Cholesterol Education Program Adults Treatment Panel III.
Results: Median intakes of vitamin D were 1.5 and 1.6 µ g/day in men and women respectively. After adjustment for confounding factors, dietary vitamin D intake was inversely associated with fasting blood glucose (β = -0.085, p = 0.004) and waist circumference (β = -0.065, p = 0.035); these associations were attenuated following further adjustment for demographics, body mass index (BMI) and dietary factors ((β = -0.066, p = 0.030) and (β = -0.065, p = 0.044), respectively. An association was observed between incidence of MetS and vitamin D intake (p trend = 0.040), independent of age, gender, smoking, physical activity; this association remained following further adjustment for BMI (p for trend = 0.044) and dietary factors (p for trend = 0.051).
Conclusion: Our findings suggest a significant inverse association between dietary vitamin D intake, MetS, and some of its components after controlling for confounding factors.
Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes.1988; 37(12): 1595-607.
Azizi F, Emami H, Salehi P, Ghanbarian A, Mirmiran P, Mirbolooki M, et al. Cardiovascular risk factors in the elderly: the Tehran Lipid and Glucose Study. J Cardiovasc Risk. 2003; 10(1):65-73.
Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA. 2002; 287(3): 356-9.
Rennie KL, McCarthy N, Yazdgerdi S, Marmot M, Brunner E. Association of the metabolic
syndrome with both vigorous and moderate physical activity. Int J Epidemiol. 2003; 32(4):600-6.
Giovannucci E, Liu Y, Hollis BW, Rimm EB. 25- hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med. 2008; 168(11): 1174-80.
Heaney RP. Functional indices of vitamin D status and ramifications of vitamin D deficiency. Am J Clin Nutr. 2004; 80(6 Suppl): 1706S-9S.
Parker J, Hashmi O, Dutton D, Mavrodaris A, Stranges S, Kandala NB, et al. Levels of vitamin D and cardiometabolic disorders: systematic review and meta-analysis. Maturitas. 2010; 65(3):225-36.
Shab-Bidar S, Neyestani TR, Djazayery A, Eshraghian MR, Houshiarrad A, Gharavi A, et al. Regular consumption of vitamin D-fortified yogurt drink (Doogh) improved endothelial biomarkers in subjects with type 2 diabetes: a randomized double-blind clinical trial. BMC Med. 2011; 9: 125.
Shab-Bidar S, Neyestani TR, Djazayery A, Eshraghian MR, Houshiarrad A, Kalayi A, et al. Improvement of vitamin D status resulted in amelioration of biomarkers of systemic inflammation in the subjects with type 2 diabetes. Diabetes Metab Res Rev. 2012; 28(5): 424-30.
Kamycheva E, Joakimsen RM, Jorde R. Intakes of calcium and vitamin d predict body mass index in the population of Northern Norway. J Nutr. 2003; 133(1): 102-6.
Liu S, Song Y, Ford ES, Manson JE, Buring JE, Ridker PM. Dietary calcium, vitamin D, and the prevalence of metabolic syndrome in middle-aged and older U.S. women. Diabetes Care. 2005;28(12): 2926-32.
Pittas AG, Dawson-Hughes B, Li T, Van Dam RM, Willett WC, Manson JE, et al. Vitamin D and calcium intake in relation to type 2 diabetes in women. Diabetes Care. 2006; 29(3): 650-6.
Azizi F, Rahmani M, Emami H, Mirmiran P, Hajipour R, Madjid M, et al. Cardiovascular risk factors in an Iranian urban population: Tehran lipid and glucose study (phase 1). Soz Praventivmed. 2002; 47(6): 408-26.
Hosseini-Esfahani F, Jessri M, Mirmiran P, Bastan S, Azizi F. Adherence to dietary recommendations and risk of metabolic syndrome: Tehran Lipid and Glucose Study. Metabolism. 2010; 59(12): 1833-42.
Kriska AM, Knowler WC, LaPorte RE, Drash AL, Wing RR, Blair SN, et al. Development of questionnaire to examine relationship of physical activity and diabetes in Pima Indians. Diabetes Care. 1990; 13(4): 401-11.
Momenan AA, Delshad M, Sarbazi N, Rezaei GN, Ghanbarian A, Azizi F. Reliability and validity of the Modifiable Activity Questionnaire (MAQ) in an Iranian urban adult population. Arch Iran Med. 2012; 15(5): 279-82.
Mirmiran P, Esfahani FH, Mehrabi Y, Hedayati M, Azizi F. Reliability and relative validity of an FFQ for nutrients in the Tehran lipid and glucose study. Public Health Nutr. 2010; 13(5): 654-62.
Ghaffarpour M, Houshyar-Rad A, Kianfar H. The Manual for household measures, cooking yields factors and edible portion of food. Tehran, Iran: Keshavarzi Press; 1999.
Azar M. Food composition table of Iran. Tehran, Iran: National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences; 1980.
Gannage-Yared MH, Azoury M, Mansour I, Baddoura R, Halaby G, Naaman R. Effects of a short-term calcium and vitamin D treatment on serum cytokines, bone markers, insulin and lipid concentrations in healthy post-menopausal women. J Endocrinol Invest. 2003; 26(8): 748-53.
Azizi F, Ghanbarian A, Madjid M, Rahmani M.Distribution of blood pressure and prevalence of hypertension in Tehran adult population: Tehran Lipid and Glucose Study (TLGS), 1999-2000. J Hum Hypertens. 2002; 16(5): 305-12.
Azizi F, Ghanbarian A, Momenan AA, Hadaegh F, Mirmiran P, Hedayati M, et al. Prevention of non-communicable disease in a population in nutrition transition: Tehran Lipid and Glucose Study phase II. Trials. 2009; 10: 5.
Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, et al. Harmonizing the
metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009; 120(16): 1640-5.
Azizi F, Hadaegh F, Khalili D, Esteghamati A, Hosseinpanah F, Delavari A, et al. Appropriate definition of metabolic syndrome among Iranian adults: report of the Iranian National Committee of Obesity. Arch Iran Med. 2010; 13(5): 426-8.
Walter W. Nutritional epidemiology. 2nd ed.Oxford, UK: Oxford University press; 1989.
Hypponen E, Boucher BJ, Berry DJ, Power C.25-hydroxyvitamin D, IGF-1, and metabolic syndrome at 45 years of age: a cross-sectional study in the 1958 British Birth Cohort. Diabetes.2008; 57(2): 298-305.
Fung GJ, Steffen LM, Zhou X, Harnack L, Tang W, Lutsey PL, et al. Vitamin D intake is inversely related to risk of developing metabolic syndrome in African American and white men and women over 20 y: the Coronary Artery Risk Development in Young Adults study. Am J Clin Nutr. 2012; 96(1): 24-9
Tai K, Need AG, Horowitz M, Chapman IM.Vitamin D, glucose, insulin, and insulin sensitivity. Nutrition. 2008; 24(3): 279-85.
Botella-Carretero JI, Alvarez-Blasco F, Villafruela JJ, Balsa JA, Vazquez C, Escobar- Morreale HF. Vitamin D deficiency is associated with the metabolic syndrome in morbid obesity. Clin Nutr. 2007; 26(5): 573-80.
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985; 28(7):412-9.
Hosseinpanah F, Pour SH, Heibatollahi M, Moghbel N, Asefzade S, Azizi F. The effects of air pollution on vitamin D status in healthy women: a cross sectional study. BMC Public Health. 2010; 10: 519.
DeLuca HF. Vitamin D: new horizons. Clin Orthop Relat Res. 1971; 78: 4-23.
Winters SJ, Chennubhatla R, Wang C, Miller JJ.Influence of obesity on vitamin D-binding protein and 25-hydroxy vitamin D levels in African American and white women. Metabolism. 2009;58(4): 438-42.
Neyestani TR, Djazayery A, Shab-Bidar S, Eshraghian MR, Kalayi A, Shariatzadeh N, et al. Vitamin D Receptor Fok-I polymorphism modulates diabetic host response to vitamin D intake: need for a nutrigenetic approach. Diabetes Care. 2013; 36(3): 550-6.
Foss YJ. Vitamin D deficiency is the cause of common obesity. Med Hypotheses. 2009; 72(3):314-21.
Perez-Lopez FR. Vitamin D metabolism and cardiovascular risk factors in postmenopausal women. Maturitas. 2009; 62(3): 248-62.
Oh JY, Barrett-Connor E. Association between vitamin D receptor polymorphism and type 2 diabetes or metabolic syndrome in community- dwelling older adults: the Rancho Bernardo Study. Metabolism. 2002; 51(3): 356-9.
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| Issue | Vol 1, No 2 (spring 2015) | |
| Section | Original Article(s) | |
| Keywords | ||
| Vitamin D Metabolic syndrome Adults Iran | ||
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