Effect of cream and yogurt butter diets on serum lipid profile in rats
Objectives: Hypercholesterolemia is a major risk factor associated with coronary heart disease. The medical society recommends the consumption of low-fat and low-cholesterol foods. The current study aimed to explore the effect of different diets with cream or yogurt butter on plasma triglyceride and cholesterol levels in rats.
Methods: Yogurt butter and sweet cream butter were produced and their fatty acid profiles were created using gas chromatography; then, the index of atherogenicity (IA) was calculated for each butter. The rats were divided into three groups, with one group being fed with standard pellets as the control group and the other two with pellets mixed with 10% cream or yogurt butter for 4 weeks. Serum lipid profile was compared between the groups.
Results: In comparison with cream butter and control groups, yogurt butter did not change serum triglycerides. The yogurt butter diet resulted in a lower total cholesterol than the other diets (p = 0.04 for cream butter and p = 0.001 for the control group). The rats fed with the yogurt diet had higher HDL cholesterol. IA decreased (p = 0.0009) and conjugated linoleic acid (p = 0.003) increased significantly in the yogurt butter compared with the cream butter group.
Conclusion: Yogurt butter improved serum lipid profile and fatty acid composition in rats. Further human trials are needed to confirm these results.
Abdel Gawad I, Elsayed EM. (2004). The hypocholesterolaemic effect of milk yoghurt and soy yoghurt containing bifidobacteria in rats fed on cholesterol-enriched diet. Int Dairy J 15:37-44.
Alizadeh A, Ehsani MR, Ezzatpanah H, Mousavi G, Darabi M, Rofehgarinejad L. (2012). Effect of cow and sheep milk diet on plasma lipids in rats. Milk Sci Int 67:349-351.
Asadi F, Shahriari A, Chahardad-Cheric M. (2010).Effect of long-term ingestion of canola oil, grae seed oil, corn oil and yogurt butter on serum, muscle and liver cholesterol status in rats. Food Chem Toxicol 48: 2454-2457.
Biong AS, Muller H, Seljeflot I, Veierod MB, Pedersen JI. (2004). A comparison of the effects of cheese and butter on serum lipids, haemostatic variables and homocystein. Br J Nutr 92(5):791-797.
Bobe G, Zimmerman S, Hammond EG, Freeman AE, Porter PA, Luhman CM. (2007). Butter composition and texture from cows with different milk fatty acid composition fed fish oil or roasted soybeans. J Dairy Sci 90: 2596 -2603.
Bucolo G, David H. (1973). Quantitative determination of serum triacylglycride by the use of enzyme. Clinical Chem 19: 476-482.
Coakley M, Ross RP, Nordgren M, Fitzgerald G, Devery R, Stanton C. (2003). Conjugated linoleic acid biosynthesis by human-derived Bifidobacterium species. J Applied Microbiology 94:138 -145.
Collomb M, Schmid A, Sieber R, Wechsler D, Ryhanen EL. (2006). Conjugated linoleic acids in milk fat : Variation and physiological effects. Int Dairy J 16:1347 -1361.
Dilmi-Bouras A. (2006).Assimilation (In vitro) of cholesterol by yogurt bacteria. Ann Agric Environ Med 13:49-53.
German JB, Dillard CJ. (2006).Composition, structure and absorption of milk lipids:A source of energy, fat-soluble nutrients and bioactive molecules. Crit Rev Food Sci Nutr 46:57-92.
Haug et al. (2008). Effects of butter naturally enriched with conjugated linoleic acid and vaccenic acid on blood lipids and LDL particle size in growing pigs. Lipids in Health and Diseas 7:31.
Kawase M, Hashimoto H, Hosoda M, Morito H. (2000). Effect of administration of fermented milk containing whey protein concentrated to rats and healthy men on serum lipids and blood pressure. J Dairy Sci 83: 255-263.
Khursheed PN, Fryer EB, Fryer HC. (1990). Effects of skim milk, skim milk yoghurt, orotic acid and uric acid on lipid metabolism in rats. J Nutr Biochem 1: 640-646.
Kim JJ, Jung TH, Ahn J, Kwak HS. (2006).Properties of cholesterol- reduced butter made with ß-cyclodextrin and added evening primrose oil and phytosterols. J Dairy Sci 89:4503-4510.
Kris Etherton PM, Derr J, Mitchell DC, Mustad VA, Russell ME, McDonnell ET, Salabsky D, Pearson TA. (1993). The role of fatty acid saturation on plasma lipids, lipoproteins, and apolipoproteins: I. Effects of whole food diets high in cocoa butter, olive oil. Soybean oil, dairy butter and milk chocolate on the plasma lipids of young men. Metabolism: Clinical and Experimental 42: 121-129.
Kumar MV, Sambaiah K, Lokesh BR. (2000). Hypocholesterolemic effect of anhydrous milk fat ghee is mediated by increasing the secretion of biliary lipids. J Nutr Biochem 11: 69-75.
Idoui T, Benhamada N, Leghouchi E. (2010). Microbial quality, physicochemical characteristics and fatty acid composition of a traditional butter produced from cow milk in East Algeria. Grasas Y Aceites 61:232 -236.
Lepage G, Roy CC. (1986). Direct transestrification of all classes of lipids in a one-step reaction. J lipid research 27:114 -120.
Lin TY, Hung TH, Cheng TS. (2005). Conjugated linoleic acid production by immobilized cells of Lactobacillus delbrueckii SSP bulgaricus and Lactobacillus acidophilus. Food Chemistry 92: 23 -28.
Lye HS, Rusul G, Liong MT. (2010). Removal of Cholesterol by Lactobacilli via Incorporation of and Conversion to Coprostanol. J Dairy Sci 93:1383-1392.
Nader R, Warnich R ,Mc Namara JR, Belcher JP, Grinstead GF, Frantz ID. (1992). Measurement of low density lipoprotein cholesterol in serum: a status report. Clinical Chemistry 38:150-160.
Nestel PJ, Chronopulos A, Cehun M. (2005). Dairy fat in cheese raises LDL cholesterol less than that in butter in mildly hypercholesterolaemic subjects. Eur J Clin Nutr 59(9): 1059-1063.
Ooi LG, Liong MT. (2010). Cholesterol lowering effects of probiotics and prebiotics. Int J Molecular Sci 11:2499-2522.
Sagdic O, Donmez M, Demirci M. (2004). Comparison of characteristics and fatty acid profiles of traditional Turkish Yayik butters produced from goats, ewes or cow milk. Food control 15:485 -490.
Samet Bali O, Ayadi MA, Attia H. (2009). Traditional Tunisian butter: physicochemical and microbial characteristics and storage stability of the oil fraction. LWT- Food Sci Tech 42:899 -905.
Skeaff CM, Williscroft K, Mann J, Chisholm A. (2004). Replacing cows with sheeps dairy fat lowers plasma cholesterol concentration in participants consuming dairy fat-rich diets. Eur J Clin Nutr 58: 250-257.
St-Onge MP, Farnworth ER, Jones P. (2000). Consumption of fermented and nonfermented dairy products: effects on cholesterol concentrations and metabolism. Am J Clin Nutr 71: 674-681.
TholstrupT, Hoy CE, Andrsen LN, Christensen DK, Sandstrom B. (2004).Does fat in milk, butter and cheese affect blood lipid and cholesterol differently? J American College Nutr 23:169-176.
Zommara M, Tachibana N, Sakono M. (1996). Whey from skim milk decreases serum cholesterol and increases antioxidant enzymes in liver and red blood cells in rat. Nutr Research 16: 293-302.
|Issue||Vol 3, No 2 (Spring 2017)|
|Butter Cholesterol Plasma lipoproteins Triglyceride|
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