Effect of tomato juice consumption on the inflammatory biomarkers of male athletes following exhaustive exercise

  • Mohammad Taherireykande Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran
  • Ahmad Saedisomeolia Tehran University of Medical Sciences, Tehran, Iran
  • Abass Ali Gaeini Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran
  • Zohre Pourahmadi School of Health and Nutrition, Tabriz University of Medical Science, Tabriz, Iran
  • Lisa G. Wood School of Biomedical Science and Pharmacy Faculty of Health and Medicine University of Newcastle
Keywords: Lycopene, Inflammatory bio-marker, Tomato juice, Exhaustive exercise



Background: Intensive exercise increases inflammatory biomarkers such as C-reactive Protein (CRP) and Interleukin 6 (IL-6). Dietary antioxidants can alter this inflammatory/oxidative state.

Objective: The aim of this study was to determine the effect of tomato juice (and not supplement) consumption as a rich source of lycopene (a potent antioxidant) on inflammatory biomarkers of male athletes following exhaustive exercise.

Methods: Thirty male university students were enrolled and randomly divided into two groups. The experimental group consumed 200 mL tomato juice daily (containing 50 mg of lycopene) for one week, and then performed exercise on treadmill at a speed of 18 km/hour till exhaustion. The control group consumed the same amount of water and performed the same exercise regimen. Blood samples were collected pre- and immediately post-exercise for analysis of IL-6, CRP and oxidant/antioxidant ratio. IL-6 and CRP were measured using ELISA. Oxidant /antioxidant ratio was measured by colorimetric assay. Statistical analysis was undertaken using SPSS-13.

Result: In the group who consumed tomato juice, CRP levels were significantly reduced post exercise compared to pre-exercise. The levels of IL-6 and oxidant/antioxidant ratio did not change after exercise in either the tomato juice or control groups.

Conclusion: Our data showed for the first time that consumption of tomato juice, which is a main source of the antioxidant lycopene, can lead to a decrease in systemic inflammation post-exercise. This may provide a useful approach for protecting against inflammation-induced muscle damage and improving exercise performance in athletes.

Keywords: Lycopene; Inflammatory bio-marker; Tomato juice; Exhaustive exercise

Author Biographies

Mohammad Taherireykande, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran


Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran

Ahmad Saedisomeolia, Tehran University of Medical Sciences, Tehran, Iran
Ahmad Saedisomeolia (PhD), Assistant Professor of Nutrition, Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
Abass Ali Gaeini, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran
Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran Professor of
Zohre Pourahmadi, School of Health and Nutrition, Tabriz University of Medical Science, Tabriz, Iran
MSC of School of Health and Nutrition, Tabriz University of Medical Science, Tabriz, Iran
Lisa G. Wood, School of Biomedical Science and Pharmacy Faculty of Health and Medicine University of Newcastle

Centre for Asthma and Respiratory Diseases

Level 2, West Wing, HMRI Building

Kookaburra Crt

New Lambton Heights, NSW, 2305




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How to Cite
Taherireykande M, Saedisomeolia A, Gaeini AA, Pourahmadi Z, Wood LG. Effect of tomato juice consumption on the inflammatory biomarkers of male athletes following exhaustive exercise. J Nutr Sci & Diet. 4(2).
Original Article(s)