Journal of Nutritional Sciences and Dietetics 2017. 3(3):.

The effects of artificial sweeteners on type 2 diabetes glycemic parameters
Mostafa Najafipour, Jafar Zareizadeh, Zohreh Razaghi, Amir Mehdizadeh, Farzad Najafipour



Type 2 diabetes is a group of heterogeneous disorders characterized by variable degrees of insulin resistance, impaired insulin secretion, and increased glucose production. A sugar substitute is a food additive that provides a sweet taste like that of sugar while containing significantly less food energy. Some sugar substitutes are naturally produced, and others produced synthetically. Those that are not produced by nature are, in general, called artificial sweeteners.


The present study was carried out due to the importance of artificial sweeteners in diabetic patients, for comparing the level of blood sugar before and after consuming such products.


 A total of 30 outpatients were included in this clinical trial study. The patients were prevented using artificial sweeteners containing diets for 3 months and use frequent diabetic diets, instead. After this period, patients were fed with diabetic especial diet containing artificial sweeteners such as sugar, biscuit and candy under the supervision of food specialist for three additional months.


 The average Fasting blood glucose of diabetic patients increased from 121.03±25.3 mg/dl to152 ± 42 mg/dl at the end of second trimester. 2 hours after feeding parameter also showed an increase from 164.4±44.4 mg/dL to 222±72 mg/dL. Furthermore, the average of HbA1C was6.89 ± 0.9 and 7.4 ±1 in the first and the second trimesters, respectively.


The results are indicative that consuming foodstuffs containing artificial sweeteners increases blood sugar in diabetic patients.


type 2 Diabetes, fasting blood glucose, 2 hour post prandial, blood glucose, Hb A1C, Artificial sweeteners


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