Tehran University of Medical Sciences Journal of Nutritional Sciences and Dietetics 2 3 2017 08 01 Comparison of serum total antioxidant capacity between subjects with and without metabolic syndrome according their body mass index 74 74 EN Atefeh Hasaninasab 1MSc Student in Health Science nutrition, Department of Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran, ath_bm@yahoo.com Alireza Esteghamati Endocrinology and Metabolism Research Center (EMRC),Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran,esteghamati@tums.ac.ir Kamal Azam Department of Epidemiology and Biostatics, School of Public Health and Institute of Public Health Research, Tehran, Iran, kazam@tums.ac.ir Somaye Yosaee Department of clinical nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran, s_yousai2006@yahoo.com Nahal Habibi MS, Department of Nutrition and Dietetics, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, n_h1362@yahoo.com Kurosh Djafarian Department of Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran 2017 01 31 2017 06 17 Background: This study aimed to determine the differences in plasma total antioxidant capacity between metabolic syndrome patients and those without metabolic syndrome with normal weight, overweight, and obesity. Methods: A case-control study was carried out among 146 men and women (aged 20-55 years) in Endocrinology Center of Tehran University of Medical Sciences. The case group included overweight/obese subjects with metabolic syndrome and the two control groups were weight-matched subjects without metabolic syndrome and normal weight subjects without metabolic syndrome. Total antioxidant capacity was determined using the colorimetric method. Results: Waist circumference and total antioxidant capacity of the case group were significantly higher than that of both control groups ((p<0.001) for both). There was no significant difference between normal and overweight/obese control groups in total antioxidant capacity level (p=0.53). Conclusion: Oxidative stress presumably is an important factor in the pathology of metabolic syndrome and total antioxidant capacity may be responsible for defense against oxidants. https://jnsd.tums.ac.ir/index.php/jnsd/article/view/74 https://jnsd.tums.ac.ir/index.php/jnsd/article/download/74/175